Myth: Taking melatonin without a doctor’s prescription is harmful
The long answer to this question depends on many factors, including dosage and individual characteristics of the body. Please note that melatonin may be contraindicated in some people for various reasons, so you should consult your doctor before taking it.
Melatonin belongs to the group of neurohormones, that is, hormones that are produced in the brain. Its main function is to control our biological rhythms, managing the transition between sleep and wakefulness.
The maximum level of melatonin synthesis usually occurs from 23:00 to 03:00, when the concentration of this hormone in the blood reaches about 200 picograms per milliliter. At this time, healthy people sleep the most soundly.
Melatonin-containing medications have been developed by humans to regulate their biological clocks. However, these drugs and medications containing melatonin have not yet been fully studied, and their effect remains relatively low.
The most compelling evidence for melatonin’s effectiveness comes from its use to treat sleep disorders in blind people and those who suffer from difficulty falling asleep and sleep-wake cycle disorders. Some studies also point to possible benefits of melatonin for jet lag.
The effects of taking melatonin without consulting a doctor depend on the amount of this hormone in the supplement or medicine. Research shows that the effects of melatonin vary depending on the dosage and can be either positive or negative for the body.
When taking melatonin in a daily dose of 0.3 to 0.5 mg, the level of this hormone in the blood remains within the natural night peak. As a result of this dosage, the effect of melatonin is comparable to its natural release, which promotes quick and quality sleep. In such quantities, melatonin is not harmful to health.
With a daily dose of 1 to 10 mg, the level of melatonin in the blood increases 3-60 times. Although melatonin itself is not toxic, at such high concentrations it has too strong an effect on the body.
People taking these dosages through supplements or medications may experience severe daytime sleepiness, decreased performance, and a drop in body temperature that may manifest as unpleasant chills.
Taking melatonin in a dosage of 0.3 to 0.5 mg is considered safe for most people and does not cause discomfort.
Some products containing melatonin may interact with certain medications. For example, caffeine and the antidepressant fluvoxamine can increase melatonin levels in the blood, increasing the risk of side effects when taken together.
Melatonin may reduce the level of nifedipine in the body. This poses certain risks because nifedipine is used to control blood pressure. If this drug does not work enough, it may be harmful to your health.
Evidence suggests that in adults without medical conditions who have difficulty sleeping or experience jet lag, melatonin at a dosage of 0.3 to 0.5 mg does not pose a threat.
However, it is recommended that you consult with your doctor before purchasing to ensure that using a melatonin supplement or medication is truly necessary.
